Artificial immunity, as a new technology, has been applied widely in virus detection system for its advantages. This paper emphasizes on these works as follows. Firstly, we analyze the disadvantages of traditional virus detection methods and new functions of artificial immune technology, and then review some typical algorithms of the existing virus detection system based on artificial immunity. Finally, a universal evaluating scheme is proposed. The purpose for this paper is to study the existent artificial immune methods and promote the new schemes emergence for virus detection system effectively.