Chemistry is very interesting, but it is often regarded as a difficult subject. Computer software can make chemistry teaching easier, and keeps the students active. This paper seeks to introduce some implications of computer softwares in chemistry classroom teaching. These softwares include Powerpoint, Chemoffice, computer simulation softwares, LabVIEW software, some computational chemistry softwares, and other chemistry softwares, such as ACD/ChemSketch, ChemDB software, Chemical Reagent Calculator, Atom Builder and Atoms, Symbols and Equations. We gave the simple directions of these softwares and presented some applicable examples.