Blackboard platform is currently used for undergraduate education in our college. To investigate its role in physiology learning, we conducted a survey on undergraduate students in nurse major. The results suggested that Blackboard platform is helpful and playing an important role in physiology learning. But compared with other learning manners, e-learning on Blackboard is neither the mostly adopted method of learning, nor the preferred means in reviewing. We conclude that Blackboard is not a substitute of textbook, but Blackboard learning may become an important complement to traditional education in undergraduate students.