Code Division Multiple Access (CDMA) is a technique in which transmission of information takes place simultaneously over the same available channel bandwidth. CDMA systems make use of spread spectrum (SS) technique for transmission of information by employing spreading codes. Each user is assigned with a unique spreading code which acts as a signature code for that individual user. The CDMA system experiences Multiple Access Interference (MAI) and Inter Symbol Interference (ISI) because of the non-orthogonality of the spreading codes. Both the MAI and ISI are the functions of auto-correlation and cross-correlation values of the spreading code respectively. In this paper, a novel orthogonal spreading code called “Orthogonal Minimum Correlation Spreading Code” (OMCSC) has been proposed which can serve a large number of users and is simultaneously expected to reduce the effect of MAI and ISI. Moreover, the Bit Error Rate (BER) performance of the proposed code has been compared with the existing codes using Additive White Gaussian Noise (AWGN) channel under multi-user scenario.