IJEM Vol. 1, No. 3, 5 Jun. 2011
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Decompressive Craniectomy, simulation, post- craniectomy hydrodynamics, deflection solution
A model of post-craniectomy intracranial pressure dynamics is proposed in this article. Defining the craniectomy distensible volume the original Monro-Kellie principle is generalized. A craniectomy compartment is added to traditional intracranial system including blood, cerebrospinal fluid, and brain parenchyma. The system equation of generalized Monro-Kellie principle is solved with 4th order runge-kutta method. Volume of the new compartment is calculated with deflection solution. The model verifies that abnormal morphology of intracranial pressure (systolic value-21mmHg and diastolic value-13mmHg) in hypertension can be reduced to a normal range (systolic value-14.5mmHg and diastolic value-13mmHg) with decompressive craniectomy. Additionally the ICP-DC Size curve provides an effective interval (about 80-200 square centimeters) of craniectomy size for practice of decompressive craniectomy.
Ketong Wang,Yun Ding,Xinyuan Zhang,Xiaoyang Zhou,"Post-craniectomy Intracranial Pressure Dynamics:A Novel Compartmental Model of Generalized Monro-Kellie Principle", IJEM, vol.1, no.3, pp.62-68, 2011. DOI: 10.5815/ijem.2011.03.10
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