Mohane Selvaraj Coumar

Work place: Centre for Bioinformatics, Pondicherry University, Pondicherry, India

E-mail: mohane@bicpu.edu.in

Website:

Research Interests: Chemistry, Computational Chemistry

Biography

Dr. Mohane Selvaraj Coumar is an Assistant Professor at the Centre for Bioinformatics, Pondicherry University. He received his M.Pharm. and Ph.D. degrees in Pharmaceutical Sciences from Panjab University, Chandigarh, India, and has over seven years of Post-doctoral research experience in Taiwan. His research interests include computer-aided drug design and medicinal chemistry, with focus on cancer drug discovery. He has to his credit over 70 national and international publications, three US and one EU patents.

Author Articles
Multi-objective Monkey Algorithm for Drug Design

By R. Vasundhara Devi S. Siva Sathya Nilabh Kumar Mohane Selvaraj Coumar

DOI: https://doi.org/10.5815/ijisa.2019.03.04, Pub. Date: 8 Mar. 2019

Swarm intelligence algorithms are designed to mimic the natural behaviors of living organisms. The birds, animals and insects exhibit extraordinary problem solving behaviors and intelligence when living in colonies or groups. These unique behaviors form the basis for the design of the Metaheuristic which are helpful in solving several real-life combinatorial optimization problems. Monkey algorithm is developed based on the unique behaviors of monkeys such as mountain and tree climbing, jumping, watching and somersaulting. This paper reports for the first time the design and development of Multi-objective Monkey Algorithm (MoMA) and its use for the design of molecules with optimal drug-like properties. Finally, the performance of the proposed MoMA for Drug design (MoMADrug) is compared with the previously disclosed Multi-objective Genetic algorithm (MoGADdrug) for the design of drug-like molecules.

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