Tong Wang; Tian Xia; Xiaoxia Cao

International Journal of Wireless and Microwave Technologies (IJWMT)

IJWMT Vol. 2, No. 5, 15 Oct. 2012

Cover page and Table of Contents: PDF (size: 151KB)

Feature Dimension Reduction Algorithm Based Prediction Method for Protein Quaternary Structure

Full Text (PDF, 151KB), PP.28-33

Views: 0 Downloads: 0

Author(s)

Tong Wang ^1,* Tian Xia ¹ Xiaoxia Cao ¹

1. Shanghai Second Polytechnic University, Shanghai, 201209, China

* Corresponding author.

DOI: https://doi.org/10.5815/ijwmt.2012.05.04

Received: 5 Jun. 2012 / Revised: 19 Jul. 2012 / Accepted: 3 Sep. 2012 / Published: 15 Oct. 2012

Index Terms

PSSM, Protein Quaternary Structure, Feature Dimension Reduction

Abstract

Knowing the quaternary structure of an uncharacterized protein often provides useful clues for finding its biological function and interaction process with other molecules in a biological system. Here, dimensionality reduction algorithm is introduced to predict the quaternary structure of proteins. Our jackknife test results indicate that it is very promising to use the dimensionality reduction approaches to cope with complicated problems in biological systems, such as predicting the quaternary structure of proteins.

Cite This Paper

Tong Wang, Tian Xia, Xiaoxia Cao,"Feature Dimension Reduction Algorithm Based Prediction Method for Protein Quaternary Structure", IJWMT, vol.2, no.5, pp.28-33, 2012. DOI: 10.5815/ijwmt.2012.05.04

Reference

[1]R. Garian. Prediction of quaternary structure from primary structure. Bioinformatics, vol. 17, p. 551-556, 2001.

[2]X. Xiao, P. Wang, K.C. Chou. Quat-2L: a web-server for predicting protein quaternary structural attributes. Molecular Diversity, 2010, in press.

[3]K.C. Chou and Y.D. Cai, Predicting protein quaternary structure by pseudo amino acid composition. Proteins, vol. 53, p. 282-289, 2003

[4]H. Kaur and G.P. Raghava. A neural-network based method for prediction of gamma-turns in proteins from multiple sequence alignment. Protein Sci, vol. 12, p. 923-929, 2003.

[5]L.J.P.v.d. Maaten, E.O. Postma, and H.J.v.d. Herik, Dimensionality Reduction: A Comparative Review. 2007.

[6]S. Mika, G. Ratsch, J. Weston, B. Scholkopf. "Fisher discriminant analysis with kernels," in: Neural Networks for Signal Processing IX: Proceedings of the 1999 IEEE Signal Processing Society Workshop Madison, WI, US, pp.41–48, 1999.